Regulation of Immunity by Gut Microbiota
Welcome to Vaishnava Lab!
Nearly 100 trillion bacteria reside in our gut, yet we rarely elicit a harmful immune and inflammatory response against them. How is such a peaceful coexistence achieved? Work in Vaishnava lab focuses on studying the interactions between microbes and the host at the molecular level that ensures this host-microbe mutualism. We use germ-free mouse models in combination with a broad array of genetic, cell biological and biochemical approaches to explore the complex interactions between intestinal bacteria and the immune system.
Lab projects are focused on understanding the role of immunity in regulating host-microbe interaction at the mucosal surface, and the molecular mechanisms by which bacteria regulate host immunity.